I like to mix up my genres like a plate of mashed potatoes, corn, mac-n-cheez, and meatloaf. When I did my King Arthur RPG "The Questing Beast" I could not help but make it anthropomorphic...just another wrinkle to the idea.
Catgirl, space, sci-fantasy. Now if I can work her into a story that is based on McBeth it will be awesome.